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- 手機(jī)：400-1016-218
- Q Q：355185756
- 郵箱：355185756@qq.com
- 地址：安徽省合肥市高新區(qū)黃山路602號(hào)合肥國家大學(xué)科技園A401室
Anti -Villin Rabbit pAb
價(jià)格：
在線咨詢
貨號(hào)：
KT012262
產(chǎn)品規(guī)格：
100 μL
Applications：
WB/IHC/IF
Species：
H/M/R,H/M/R,H/M/R
購買數(shù)量：
產(chǎn)品詳情
操作說明
注意事項(xiàng)
Product Information
|
Description |
Villin rabbit polyclonal antibody |
|
Protein full name |
Villin-1 |
|
Synonyms |
VIL1, VIL, Villin 1, D2S1471 |
|
Immunogen |
Recombinant protein corresponding to Human Villin |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Subcellular location |
Cytoplasm |
|
Predicted MW. |
93 kDa |
|
Observed MW. |
95 kDa |
|
Uniprot ID |
P09327, Q62468 |
Applications
|
Applications |
Species |
Dilution |
Positive Sample |
|
WB |
Human, Mouse, Rat |
1: 1000-1: 2000 |
small intestine, colon, kidney |
|
IHC/IF |
Human, Mouse, Rat |
1: 500-1: 3000 |
colon, gall bladder, kidney, small intestine |
Background
Villin 1 (VIL1) is a 95-kd F-actin bundling and severing protein and its expression is restricted to epithelial cells with a brush border, like epithelial cells of the intestinal mucosa, gall bladder, renal proximal tubules and ductuli efferentes of the testis. VIL1 has been reported to be an epithelial cell-specific anti-apoptotic protein, and to have an important function in regulating actin dynamics, cell morphology, epithelial-to-mesenchymal transitions, cell migration and cell survival. In addition, VIL1 is a useful diagnostic marker for of various cancer, like cervical and endometrial adenocarcinomas, renal cell carcinoma. VIL1 was recently identified as a novel biomarker predictive for postoperative recurrence and poorer prognosis of high serum AFP associated HCC.
Images
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Western blot analysis of villin at dilution of 1: 1000 |
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Immunohistochemistry of paraffin embedded human colon using villin (GB111209) at dilution of 1: 1500 (400x lens) |
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Immunohistochemistry of paraffin embedded mouse kidney using villin (GB111209) at dilution of 1: 1500 (400x lens) |
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Immunohistochemistry of paraffin embedded rat gall bladder using villin (GB111209) at dilution of 1: 1500 (400x lens) |
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Immunohistochemistry of paraffin embedded rat small intestine using villin (GB111209) at dilution of 1: 1500 (400x lens) |
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Immunofluorescence of paraffin embedded human colon using villin (GB111209) at dilution of 1: 1500 (400x lens) |
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Immunofluorescence of paraffin embedded mouse kidney using villin (GB111209) at dilution of 1: 1500 (400x lens) |
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Immunofluorescence of paraffin embedded rat gall bladder using villin (GB111209) at dilution of 1: 1500 (400x lens) |
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Immunofluorescence of paraffin embedded rat small intestine using villin (GB111209) at dilution of 1: 1500 (400x lens) |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol |
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合肥萬物生物科技有限公司
客服熱線：400-1016-218
QQ：355185756
地址：安徽省合肥市高新區(qū)黃山路602號(hào)合肥國家大學(xué)科技園A401室