服務(wù)熱線(xiàn)
400-1016-218
聯(lián)系方式
- 手機(jī)：400-1016-218
- Q Q：355185756
- 郵箱：355185756@qq.com
- 地址：安徽省合肥市高新區(qū)黃山路602號(hào)合肥國(guó)家大學(xué)科技園A401室
Anti -S100A9 Rabbit pAb
價(jià)格：
在線(xiàn)咨詢(xún)
貨號(hào)：
KT012257
產(chǎn)品規(guī)格：
100 μL
Applications：
IHC/IF
Species：
H,H
購(gòu)買(mǎi)數(shù)量：
產(chǎn)品詳情
操作說(shuō)明
注意事項(xiàng)
Product Information
|
Description |
S100A9 rabbit polyclonal |
|
Protein full name |
Protein S100-A9 |
|
Synonyms |
Calgranulin-B, Calprotectin L1H subunit, Leukocyte L1 complex heavy chainMRP-14, p14, S100 calcium-binding protein A9, S100A9, CAGB, CFAG, MRP14 |
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to Human S100A9 |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Subcellular location |
Cell membrane, Secreted |
|
Uniprot ID |
P06702 |
Applications
|
Applications |
Species |
Dilution |
Positive Tissue |
|
IHC |
Human |
1: 1000-1: 2000 |
colon, colon cancer |
|
IF |
Human |
1: 500-1: 1000 |
colon, colon cancer |
Background
S100A9 is a calcium- and zinc-binding protein which plays a prominent role in the regulation of inflammatory processes and immune response. It can induce neutrophil chemotaxis, adhesion, can increase the bactericidal activity of neutrophils by promoting phagocytosis via activation of SYK, PI3K/AKT, and ERK1/2 and can induce degranulation of neutrophils by a MAPK-dependent mechanism. Predominantly found as calprotectin (S100A8/A9) which has a wide plethora of intra- and extracellular functions. The intracellular functions include: facilitating leukocyte arachidonic acid trafficking and metabolism, modulation of the tubulin-dependent cytoskeleton during migration of phagocytes and activation of the neutrophilic NADPH-oxidase. The extracellular functions involve proinfammatory, antimicrobial, oxidant-scavenging and apoptosis-inducing activities.Can act as a potent amplifier of inflammation in autoimmunity as well as in cancer development and tumor spread.
Images
|
|
Immunohistochemistry analysis of paraffin-embedded human colon using S100A9 at dilution of 1: 2000 |
|
Immunohistochemistry analysis of paraffin-embedded human colon cancer using S100A9 (GB111079) at dilution of 1: 2000 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
凡合肥萬(wàn)物生物科技有限公司銷(xiāo)售的產(chǎn)品均有嚴(yán)格的質(zhì)量保證。如發(fā)現(xiàn)產(chǎn)品存在包裝規(guī)格疑問(wèn)，請(qǐng)于收貨之日起七日內(nèi)向我公司總部或當(dāng)?shù)剞k事處提出，并請(qǐng)保證該產(chǎn)品，以備本公司進(jìn)行核對(duì)檢驗(yàn)。如果發(fā)現(xiàn)有質(zhì)量問(wèn)題，請(qǐng)于收貨后一月內(nèi)保留產(chǎn)品50%以上的量，以便本公司回收產(chǎn)品進(jìn)行質(zhì)檢，確認(rèn)產(chǎn)品質(zhì)量。如逾期，則視為已經(jīng)對(duì)本公司產(chǎn)品進(jìn)行驗(yàn)收。 聲明：如發(fā)生產(chǎn)品索賠事宜，本公司僅在產(chǎn)品價(jià)格范圍內(nèi)酌情賠償，恕不接受超出產(chǎn)品價(jià)格范圍之賠償?？蛻?hù)在使用過(guò)程中有任何技術(shù)問(wèn)題可以撥打技術(shù)售后服務(wù)電話(huà)我們隨時(shí)給予解答。
合肥萬(wàn)物生物科技有限公司
客服熱線(xiàn)：400-1016-218
QQ：355185756
地址：安徽省合肥市高新區(qū)黃山路602號(hào)合肥國(guó)家大學(xué)科技園A401室