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Anti -N Cadherin Rabbit pAb

價(jià)格: 在線咨詢
貨號(hào):
KT011886
產(chǎn)品規(guī)格:
100 μL
Applications:
WB
Species:
HMR
購(gòu)買數(shù)量:
產(chǎn)品詳情 操作說(shuō)明 注意事項(xiàng)

Product Information


Description

N Cadherin rabbit polyclonal antibody

Protein full name

Cadherin-2

Synonyms

Neural cadherin, N-cadherin, CD325, CDw325, Cadherin 2 N cadherin neuronal, CDHN, Cdh2, Cadherin 2 type 1, NCAD, N cadherin 1

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse N Cadherin

Isotype

IgG

Purity

Affinity purification

Predicted MW.

100 kDa

Observed MW.

140 kDa

Uniprot ID

P19022, P15116, Q9Z1Y3




Applications


Applications

Species

Dilution

Positive Tissue

WB

Human, Mouse, Rat

1: 500-1: 1000

skeletai muscle, testis




Background


N-cadherin (neuronal cadherin; or CDH2/cadherin 2) is a calcium-binding, single pass transmembrane cell adhesion molecule (CAM) that mediate calcium-dependent intercellular adhesion. Cadherins are involved in controlling morphogenetic movements during development and regulate cell surface adhesion through homotypic adhesion with the same cadherin species. N-cadherin's function is dependent on its association with the actin-cytoskeleton and is mediated through interactions between the C-terminal region of N-cadherin and the cytoplasmic catenin proteins. The stability of this association is regulated by phosphorylation and dephosphorylation of beta-catenin. Further, N-cadherin is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. 




Images


Picture 1.png

Western blot analysis of CDH2 (GB111009) at dilution of 1: 500




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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