Anti -OB Cadherin Rabbit pAb

價(jià)格：在線咨詢

貨號：

KT011882

產(chǎn)品規(guī)格：

100 μL

Applications：

Species：

HMR

品牌：

萬物

購買數(shù)量：

立即詢價(jià) 在線咨詢 400-1016-218

產(chǎn)品詳情操作說明注意事項(xiàng)

Product Information

Description	OB Cadherin rabbit polyclonal antibody
Protein full name	Cadherin-11
Synonyms	OSF-4, Osteoblast cadherin, OB-cadherin, Cdh11, CAD11, Cadherin 11 type 2
Immunogen	KLH conjugated Synthetic peptide corresponding to Mouse OB Cadherin
Isotype	IgG
Purity	Affinity purification
Predicted MW.	88 kDa
Observed MW.	120 kDa
Uniprot ID	P55287, P55288, F1MAH6

Applications

Applications	Species	Dilution	Positive Tissue
WB	Human, Mouse, Rat	1: 500-1: 1000	brain, lung, testis

Background

The cadherin super family comprises a large number of membrane glycoproteins with one or more cadherin repeats, which are involved in Ca2+ dependent cell-cell adhesion. Cadherin-11, also known as OB-cadherin, is a type II classical cadherin. Classical cadherins are type I transmembrane proteins with an N-terminal extracellular domain containing five tandem cadherin repeats and a C-terminal cytoplasmic domain with a characteristic sequence for binding to catenins. Type I cadherins differ from type II cadherins by the presence of the HAV tripeptide motif in the most N-terminal cadherin repeat. Classic cadherins mediate cell-cell adhesion preferentially via homotypic interactions and form adherens juctions that have beta -catenin and p120 (ctn) at the cytoplasmic side of the junction. Homotypic cadherin interactions also transduce outside-in and inside-out cell signals.

Images

Western blot analysis of OB-Cadherin (GB111008) at dilution of 1: 500

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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