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Anti -KDS Rabbit pAb

價格: 在線咨詢
貨號:
KT012272
產(chǎn)品規(guī)格:
100ul
Applications:
IHC/IF
Species:
H
購買數(shù)量:
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Product Information


Description

KDS rabbit polyclonal antibody

Protein full name

Serine/threonine-protein kinase TAO3

Synonyms

CTCL-associated antigen HD-CL-09, hKFC-A, Dendritic cell-derived protein kinase, DPK, JNK/SAPK-inhibitory kinase, JIK, KDS, Jun kinase-inhibitory kinase, TAOK3, MAP3K18

Immunogen

KLH conjugated Synthetic peptide corresponding to Human KDS

Isotype

IgG

Purity

Affinity purification

Subcellular location

Cell membrane, Cytoplasm

Uniprot ID

Q9H2K8




Applications


Applications

Species

Dilution

Positive Sample

IHC/IF

Human

1: 500-1: 1000

breast cancer, colon cancer




Background


TAOK3 (Serine/threonine-protein kinase TAO3) is also named as DPK, JIK, KDS, MAP3K18 and belongs to the STE Ser/Thr protein kinase family. It acts as an activator of the p38/MAPK14 stress-activated MAPK cascade. In response to DNA damage, it is involved in the G2/M transition DNA damage checkpoint by activating the p38/MAPK14 stress-activated MAPK cascade, probably by mediating phosphorylation of upstream MAP2K3 and MAP2K6 kinases. And this protein can be autophosphorylated.




Images


Immunohistochemistry of paraffin embedded human breast cancer using TAOK3at dilution of 1:550 (400x lens)

Immunohistochemistry of paraffin embedded human colon cancer using TAOK3 at dilution of 1:550 (400x lens)




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.


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