Anti -MEK2 Rabbit pAb

價格：在線咨詢

貨號：

KT012258

產(chǎn)品規(guī)格：

100ul

Applications：

WB|IHC/IF

Species：

H/M/R,M/R

品牌：

萬物

購買數(shù)量：

立即詢價在線咨詢 400-1016-218

產(chǎn)品詳情操作說明注意事項

Product Information

Description	MEK2 rabbit polyclonal antibody
Protein full name	Dual specificity mitogen-activated protein kinase kinase 2
Synonyms	MAP kinase kinase 2, Prkmk2 ,Mek2, Mkk2, Map2k2, ERK activator kinase 2, MAPK/ERK kinase 2, MAPKK 2, PRKMK 2, PRKMK2 V
Immunogen	Recombinant protein corresponding to Mouse MEK2
Isotype	IgG
Purity	Affinity purification
Subcellular location	Cytoplasm
Predicted MW.	44 kDa
Observed MW.	48 kDa
Uniprot ID	P36507, Q63932, P36506

Applications

Applications	Species	Dilution	Positive Sample
WB	Human, Mouse, Rat	1: 500-1: 1000	lung, brain
IHC/IF	Mouse, Rat	1: 500-1: 2000	brain, lung, spleen

Background

MAP kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase. Mutations in this gene cause cardiofaciocutaneous syndrome (CFC syndrome), a disease characterized by heart defects, mental retardation, and distinctive facial features similar to those found in Noonan syndrome. The inhibition or degradation of this kinase is also found to be involved in the pathogenesis of Yersinia and anthrax.

Images

	Western blot analysis of MEK2 at dilution of 1: 500
	Immunohistochemistry of paraffin embedded mouse brain using MEK2 at dilution of 1: 2000 (350x lens)
	Immunohistochemistry of paraffin embedded mouse brain using MEK2 at dilution of 1: 2000 (400x lens)
	Immunohistochemistry of paraffin embedded rat brain using MEK2 at dilution of 1: 2000 (400x lens)
	Immunohistochemistry of paraffin embedded rat lung using MEK2 at dilution of 1: 2000 (400x lens)
	Immunohistochemistry of paraffin embedded rat spleen using MEK2 at dilution of 1: 2000 (400x lens)

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

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