Anti -WDFY3 Rabbit pAb

價格：在線咨詢

貨號：

KT012176

產(chǎn)品規(guī)格：

100 μL

Applications：

IHC/IF

Species：

品牌：

萬物

購買數(shù)量：

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產(chǎn)品詳情操作說明注意事項

Product Information

Description	WDFY3 rabbit polyclonal antibody
Protein full name	WD repeat and FYVE domain-containing protein 3
Synonyms	ALFY, Autophagy linked FYVE protein, KIAA0993, WDFY3, ZFYVE25, BWF1
Immunogen	KLH conjugated Synthetic peptide corresponding to Mouse WDFY3
Isotype	IgG
Purity	Affinity purification
Subcellular location	Cytoplasm, Membrane, Nucleus
Uniprot ID	Q8IZQ1

Applications

Applications	Species	Dilution	Positive Sample
IHC/IF	Human	1: 400-1: 1300	colon, colon cancer

Background

WDFY3 also called ALFY, is a phosphatidylinositol 3-phosphate-binding protein that functions as a master conductor for aggregate clearance by autophagy.This protein shuttles from the nuclear membrane to colocalize with aggregated proteins, where it complexes with other autophagic components to achieve macroautophagy-mediated clearance of these aggregated proteins. However, it is not necessary for starvation-induced macroautophagy.

Images

	Immunohistochemistry of paraffin embedded human colon using WDFY3 (GB111969) at dilution of 1:700 (400x lens)
	Immunohistochemistry of paraffin embedded human colon cancer using WDFY3 (GB111969) at dilution of 1:700 (400x lens)

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer	PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.

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