Anti -Lin28A Rabbit pAb

價格：在線咨詢

貨號：

KT012127

產(chǎn)品規(guī)格：

100 μL

Applications：

Species：

M/R

品牌：

萬物

購買數(shù)量：

立即詢價在線咨詢 400-1016-218

產(chǎn)品詳情操作說明注意事項

Product Information

Description	Lin28A rabbit polyclonal antibody
Protein full name	Protein lin-28 homolog A
Synonyms	Lin-28A, Testis-expressed protein 17, Lin28a, Lin28, Tex17
Immunogen	Recombinant protein corresponding to Mouse Lin28A
Isotype	IgG
Purity	Affinity purification
Predicted MW.	23 kDa
Observed MW.	28 kDa
Uniprot ID	Q8K3Y3

Applications

Applications	Species	Dilution	Positive Sample
WB	Mouse, Rat	1: 500-1: 1000	liver, skeletal muscle, testis

Background

LIN28A/B are expressed in various cancers and ES cells. LIN28 is a cytoplasmic protein, that acts as a 'translational enhancer', driving specific mRNAs to polysomes and thus increasing the efficiency of protein synthesis. LIN28 is a negative regulator of microRNA (miRNA) biogenesis by specifically binding the precursor of let-7 (pre-let-7). Let-7 miRNAs have been implicated in repression of oncogenes such as ras and myc. LIN28 expression decreases during differentiation of ES cells or upon induction of neuronal differentiation by retinoic acid.

Images

Picture 1.png

Western blot analysis of Lin28A (GB111416) at dilution of 1: 500

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer	PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.

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