Anti -FEN1 Rabbit pAb

價格：在線咨詢

貨號：

KT012121

產(chǎn)品規(guī)格：

100ul

Applications：

Species：

H/M

品牌：

萬物

購買數(shù)量：

立即詢價在線咨詢 400-1016-218

產(chǎn)品詳情操作說明注意事項(xiàng)

Product Information

Description	FEN1 rabbit polyclonal antibody
Protein full name	Flap endonuclease 1
Synonyms	FEN-1, Flap structure-specific endonuclease 1, Fen1, Fen-1, DNase IV, flap structure endonuclease 1, hFEN 1, Maturation factor 1, MF1, RAD2
Immunogen	Recombinant protein corresponding to Mouse FEN1
Isotype	IgG
Purity	Affinity purification
Predicted MW.	42 kDa
Observed MW.	45 kDa
Uniprot ID	P39748, P39749

Applications

Applications	Species	Dilution	Positive Sample
WB	Human, Mouse	1: 500-1: 1000	lung, testis, small intestine

Background

FEN1(Flap endonuclease-1) is the prototypical member of the 5’-nuclease superfamily, whose activities span a range of cellular pathways involved in DNA replication and genome maintenance . FEN1 is a structure-selective metallonuclease essential for Okazaki fragment maturation through efficient removal of 5’ flaps resulting from strand displacement during lagging-strand synthesis. FEN1 is overexpressed in multiple cancer types, and has been suggested both as a biomarker relating to prognosis and disease progression and as a potential therapeutic target.

Images

Picture 1.png

Western blot analysis of FEN1 (GB111455) at dilution of 1: 500

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer	PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.

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