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Anti -Cathepsin K Rabbit pAb

價格: 在線咨詢
貨號:
KT012034
產(chǎn)品規(guī)格:
100 μL
Applications:
IHC/IF
Species:
M/R
購買數(shù)量:
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Product Information


Description

Cathepsin K rabbit polyclonal antibody

Protein full name

Cathepsin K

Synonyms

Ctsk, Procathepsin K, Cathepsin K, Cathepsin O, Cathepsin X, CTSO

Immunogen

Recombinant protein corresponding to Mouse Cathepsin K

Isotype

IgG

Purity

Affinity purification

Subcellular location

Cytoplasm

Uniprot ID

P55097, O35186




Applications


Applications

Species

Dilution

Positive Sample

IHC/IF

Mouse, Rat

1: 1000-1: 2000

bone




Background


The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis an autosomal recessive disease characterized by osteosclerosis and short stature.




Images


Immunohistochemistry of paraffin embedded mouse bone using Gathepsin-K (GB111276) at dilution of 1:2200 (400x lens)

Immunohistochemistry of paraffin embedded rat bone using Gathepsin-K (GB111276) at dilution of 1:2200 (400x lens)




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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