Anti -GRP94 Rabbit pAb

價格：在線咨詢

貨號：

KT011917

產(chǎn)品規(guī)格：

100 μL

Applications：

Species：

HMR

品牌：

萬物

購買數(shù)量：

立即詢價在線咨詢 400-1016-218

產(chǎn)品詳情操作說明注意事項

Product Information

Description	GRP94 rabbit polyclonal antibody
Protein full name	Endoplasmin
Synonyms	94 kDa glucose-regulated protein, GRP-94, ERp99, Heat shock protein 90 kDa beta member 1, Polymorphic tumor rejection antigen 1, Tumor rejection antigen gp96, Hsp90b1, GRP94, Tra-1, Tra1
Immunogen	Recombinant protein corresponding to Mouse GRP94
Isotype	IgG
Purity	Affinity purification
Predicted MW.	92 kDa
Observed MW.	100 kDa
Uniprot ID	P14625, P08113, Q66HD0

Applications

Applications	Species	Dilution	Positive Sample
WB	Human, Mouse, Rat	1: 500-1: 1000	lung, brain

Background

GRP94 is a 803 amino acid protein belonging to the heat shock protein 90 family. It acts as a molecular chaperone that functions in the processing and transport of secreted proteins. GRP94 and its N-terminal fragment stimulates CTL expansion and maturation of human monocyte-derived dendritic cells (MDDC). It plays a central role in innate as well as acquired immunity, maturation and chemotaxis of dendritic cells, Ab production, cross-priming, as a potential marker in breast cancer and is a peptide acceptor in endoplasmic reticulum and an accessory to peptide loading of MHC class I molecules. Expression of GRP94 suppressed A23187-induced apoptosis and stabilized calcium homeostasis. GRP94 is expressed in melanoma or liver metastases of colon carcinoma cells, human gastric carcinoma BGC-823 cells.

Images

Picture 1.png

Western blot analysis of GRP94 (GB111280) at dilution of 1: 500

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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