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Anti -Cyclin A1 Rabbit pAb

價(jià)格: 在線咨詢
貨號(hào):
KT011852
產(chǎn)品規(guī)格:
100 μL
Applications:
IHC/IF
Species:
M,R
購(gòu)買數(shù)量:
產(chǎn)品詳情 操作說明 注意事項(xiàng)

Product Information


Description

Cyclin A1 rabbit polyclonal antibody

Protein full name

Cyclin-A1

Synonyms

Ccna1, G2/mitotic specific cyclin A1

Immunogen

Recombinant protein corresponding to Mouse Cyclin A1

Isotype

IgG

Purity

Affinity purification

Subcellular location

Cytoplasm, Nucleus

Uniprot ID

Q61456




Applications


Applications

Species

Dilution

Positive Sample

IHC/IF

Mouse, Rat

1: 400-1: 800

testis




Background


The critical role that the family of regulatory proteins known as cyclins play in eukaryotic cell cycle regulation is well established. The best-characterized cyclin complex is the mitotic cyclin B/Cdc2 p34 kinase, the active component of maturing promoting factor. Cyclin A accumulates prior to cyclin B in the cell cycle, appears to be involved in control of S phase and has been shown to associate with cyclin-dependent kinase-2 (Cdk2). In addition, cyclin A has been implicated in cell transformation and is found in complexes with E1A, transcription factors DRTF1 and E2F and retinoblastoma protein, p110. A second form of cyclin A, named cyclin A1 because of its high sequence homology to Xenopus cyclin A1, is most highly expressed in germ cells.




Images


Picture 1.png

Immunohistochemistry of paraffin embedded mouse testis using CCNA1 (GB111921) at dilution of 1:400 (300x lens)




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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