服務(wù)熱線
400-1016-218
聯(lián)系方式
- 手機(jī)：400-1016-218
- Q Q：355185756
- 郵箱：355185756@qq.com
- 地址：安徽省合肥市高新區(qū)黃山路602號(hào)合肥國(guó)家大學(xué)科技園A401室
Anti -P35 Rabbit pAb
價(jià)格：
在線咨詢
貨號(hào)：
KT011836
產(chǎn)品規(guī)格：
100 μL
Applications：
WB
Species：
M,R
購(gòu)買數(shù)量：
產(chǎn)品詳情
操作說明
注意事項(xiàng)
Product Information
|
Description |
P35 rabbit polyclonal antibody |
|
Protein full name |
Cyclin-dependent kinase 5 activator 1 |
|
Synonyms |
CDK5 activator 1, Cyclin-dependent kinase 5 regulatory subunit 1, TPKII regulatory subunit, Tau protein kinase II 23 kDa subunit, Cdk5r1, CDK5P35, Neuronal CDK5 activator |
|
Immunogen |
Recombinant protein corresponding to Mouse P35 |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Predicted MW. |
34 kDa |
|
Observed MW. |
35 kDa |
|
Uniprot ID |
P61809, P61810 |
Applications
|
Applications |
Species |
Dilution |
Positive Sample |
|
WB |
Mouse, Rat |
1: 500-1: 1000 |
hippocampus, brain, spinal cord, cerebellum |
Background
Cyclin dependent kinase-5 (Cdk5), is an atypical but essential member of the Cdk family of proline-directed serine/threonine kinases. CDK5R1 encodes p35, a specific activator of the serine/threonine kinase CDK5, which plays a central role in neuronal migration and differentiation during central nervous system development. The p35 form of this protein is proteolytically cleaved by calpain, generating a p25 form.The cleavage of p35 into p25 results in relocalization of the protein from the cell periphery to nuclear and perinuclear regions. P25 deregulates CDK5 activity by prolonging its activation and changing its cellular location.
Images
|
|
Western blot analysis of P25 (GB111614) at dilution of 1: 500 |
|
|
Western blot analysis of P35 (GB111614) at dilution of 1: 500 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
凡合肥萬物生物科技有限公司銷售的產(chǎn)品均有嚴(yán)格的質(zhì)量保證。如發(fā)現(xiàn)產(chǎn)品存在包裝規(guī)格疑問，請(qǐng)于收貨之日起七日內(nèi)向我公司總部或當(dāng)?shù)剞k事處提出，并請(qǐng)保證該產(chǎn)品，以備本公司進(jìn)行核對(duì)檢驗(yàn)。如果發(fā)現(xiàn)有質(zhì)量問題，請(qǐng)于收貨后一月內(nèi)保留產(chǎn)品50%以上的量，以便本公司回收產(chǎn)品進(jìn)行質(zhì)檢，確認(rèn)產(chǎn)品質(zhì)量。如逾期，則視為已經(jīng)對(duì)本公司產(chǎn)品進(jìn)行驗(yàn)收。 聲明：如發(fā)生產(chǎn)品索賠事宜，本公司僅在產(chǎn)品價(jià)格范圍內(nèi)酌情賠償，恕不接受超出產(chǎn)品價(jià)格范圍之賠償。客戶在使用過程中有任何技術(shù)問題可以撥打技術(shù)售后服務(wù)電話我們隨時(shí)給予解答。
合肥萬物生物科技有限公司
客服熱線：400-1016-218
QQ：355185756
地址：安徽省合肥市高新區(qū)黃山路602號(hào)合肥國(guó)家大學(xué)科技園A401室