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Anti -TRAF4 Rabbit pAb

價(jià)格: 在線咨詢
貨號:
KT012204
產(chǎn)品規(guī)格:
100 μL
Applications:
WB | IHC | IF
Species:
H,M,R | M,R | M,R
購買數(shù)量:
產(chǎn)品詳情 操作說明 注意事項(xiàng)

Product Information


Description

TRAF4 rabbit polyclonal

Protein full name

TNF receptor-associated factor 4

Synonyms

Cysteine-rich motif associated to RING and Traf domains protein 1, Traf4, Cart1, MLN62,  tumor necrosis receptor-associated factor 4A

Immunogen

KLH conjugated Synthetic peptide corresponding to Human TRAF4

Isotype

IgG

Purity

Affinity purification

Subcellular location

Nucleus, Cytoplasm

Predicted MW.

53 kDa

Observed MW.

53 kDa

Uniprot ID

Q9BUZ4, Q61382, A8DYU9




Applications


Applications

Species

Dilution

Positive Tissue

WB

Human, Mouse, Rat

1: 500-1: 1000

thymus, brain, lymph nodes

IHC

Mouse, Rat

1: 250-1: 500

lymphoid, thymus

IF

Mouse, Rat

1: 150-1: 300

lymphoid, thymus




Background


The tumor necrosis factor receptor-associated factor (TRAF) family is a group of signaling adaptors which participate in various signaling pathways through binding of the tumor necrosis factor receptor super family. As one of the important member of TRAF family proteins, TRAF4 was initially isolated from breast carcinomas and identified as the first member of the TRAF family to be up-regulated in human carcinomas. TRAF4 is required during embryo genesis in key biological processes including the formation of the trachea, the development of the axial skeleton, and the closure of the neural tube. TRAF4 deficiency leads to severe developmental alterations.




Images


image.png

Western blot analysis of TRAF4 (GB111015) at dilution of 1: 1000

Lane 1: Hela cell lysate

Lane 2: Jurkat cell lysate

Lane 3: THP-1 cell lysate

Lane 4: Mouse thymus tissue lysate

Lane 5: Mouse brain tissue lysate

Lane 6: Mouse lymph nodes tissue lysate

Lane 7: Rat thymus tissue lysate

Lane 8: Rat brain tissue lysate

Lane 9: Rat lymph nodes tissue lysate

image.png

Immunohistochemistry analysis of paraffin-embedded mouse lymphoid using TRAF4 (GB111015) at dilution of 1: 250

image.png

Immunohistochemistry analysis of paraffin-embedded rat thymus using TRAF4 (GB111015) at dilution of 1: 250




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).



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