Anti -ADAR1 Rabbit pAb

價格：在線咨詢

貨號：

KT012090

產(chǎn)品規(guī)格：

100 μL

Applications：

Species：

品牌：

萬物

購買數(shù)量：

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產(chǎn)品詳情操作說明注意事項

Product Information

Description	ADAR1 rabbit polyclonal antibody
Protein full name	Double-stranded RNA-specific adenosine deaminase
Synonyms	DRADA, RNA adenosine deaminase 1, Adar, Adar1, 136kDa double stranded RNA binding protein, AGS6, Adenosine deaminase acting on RNA 1 A, Interferon inducible protein 4, RNA adenosine deaminase 1
Immunogen	Recombinant protein corresponding to Mouse ADAR1
Isotype	IgG
Purity	Affinity purification
Predicted MW.	130 kDa
Observed MW.	110 kDa
Uniprot ID	P55265

Applications

Applications	Species	Dilution	Positive Sample
WB	Human	1: 500-1: 1000	293T, Jurkat, HepG2, HeLa, DU145

Background

ADAR1 is also named as ADAR1, DSRAD, G1P1, IFI4. It convert selected adenosine residues into inosine in substrate RNAs containing a relatively short dsRNA region. The human ADAR1 gene specifies two size forms of RNA-specific adenosine deaminase, an interferon (IFN) inducible ～150 kDa protein and a constitutively expressed N-terminally truncated ～110 kDa protein, encoded by transcripts with alternative exon 1 structures that initiate from different promoters. It has 5 isoforms produced by alternative promoter usage and alternative splicing. Defects in ADAR are a cause of dyschromatosis symmetrical hereditaria (DSH).ADAR1 can form respective homodimers, and this association is essential for its enzymatic activities.

Images

Picture 1.png

Western blot analysis of ADAR1 (GB111458) at dilution of 1: 500

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer	PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.

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