Anti -PABP Rabbit pAb

價格：在線咨詢

貨號：

KT012060

產(chǎn)品規(guī)格：

100 μL

Applications：

IHC/IF

Species：

HMR/MR

品牌：

萬物

購買數(shù)量：

立即詢價在線咨詢 400-1016-218

產(chǎn)品詳情操作說明注意事項

Product Information

Description	PABP rabbit polyclonal antibody
Protein full name	Polyadenylate-binding protein 1
Synonyms	PABP-1, Poly(A)-binding protein 1, Pabpc1, Pabp1
Immunogen	Recombinant protein corresponding to Mouse PABP
Isotype	IgG
Purity	Affinity purification
Subcellular location	Nucleus, Cytoplasm
Predicted MW.	71 kDa
Observed MW.	71 kDa
Uniprot ID	P29341, Q9EPH8

Applications

Applications	Species	Dilution	Positive Sample
WB	Human, Mouse, Rat	1: 500-1: 1000	liver, testis, brain
IHC/IF	Mouse, Rat	1: 1000-1: 4000	testis

Background

PABPC1 binds the poly(A) tail of mRNA. It may be involved in cytoplasmic regulatory processes of mRNA metabolism such as pre-mRNA splicing. Its function in translational initiation regulation can either be enhanced by PAIP1 or repressed by PAIP2. PABPC1 can probably bind to cytoplasmic RNA sequences other than poly(A) in vivo. It may be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain.

Images

	Western blot analysis of pabp1 (GB111164) at dilution of 1: 500
	Immunohistochemistry of paraffin embedded mouse testis using pabp1 (GB111164) at dilution of 1: 1200 (400x lens)
	Immunohistochemistry of paraffin embedded rat testis using pabp1 (GB111164) at dilution of 1: 1200 (400x lens)
	Immunofluorescence of paraffin embedded mouse testis using pabp1 (GB111164) at dilution of 1: 3913 (400x lens)
	Immunofluorescence of paraffin embedded rat testis using pabp1 (GB111164) at dilution of 1: 3913 (400x lens)

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.

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