Anti -Dopamine Transporter Rabbit pAb

價格：在線咨詢

貨號：

KT012000

產(chǎn)品規(guī)格：

100 μL

Applications：

Species：

品牌：

萬物

購買數(shù)量：

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產(chǎn)品詳情操作說明注意事項

Product Information

Description	Dopamine Transporter rabbit polyclonal antibody
Protein full name	Sodium-dependent dopamine transporter
Synonyms	DA transporter, DAT, Solute carrier family 6 member 3, Slc6a3, Dat, Dat1
Immunogen	Recombinant protein corresponding to Mouse Dopamine Transporter
Isotype	IgG
Purity	Affinity purification
Predicted MW.	69 kDa
Observed MW.	69 kDa
Uniprot ID	Q61327, P23977

Applications

Applications	Species	Dilution	Positive Sample
WB	Mouse, Rat	1: 500-1: 1000	brain, cortex, hippocampus, cerebellum

Background

DAT1, also known as SLC6A3 and Sodium-dependent dopamine transporter, is a sodium and chloride-dependent dopamine transporter belonging to the solute carrier family 6. Dopamine transporters are distributed widely across the brain in regions with high dopaminergic activity, such as the striatum and substantia nigra. These transporters effectively provide fast acting clearance of dopamine, adrenalin and noradrenalin from the synaptic cleft, thus terminating the neurotransmitter signal. DATs have been found to interact with PRKCABP, TGFB1I1, SLC18A2 and the N-terminus of SYNGR3. DATs are also the target proteins for psychomotor stimulants such as amphetamines and cocaine. Research has implicated DATs as useful markers in detecting depression, schizophrenia, Parkinson's disease and drug abuse.

Images

Picture 1.png

Western blot analysis of SLC6A3 (GB111215) at dilution of 1: 500

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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