Anti -kynurenine 3-monooxygenase Rabbit pAb

價(jià)格：在線咨詢

貨號：

KT011993

產(chǎn)品規(guī)格：

100ul

Applications：

WB|IHC/IF

Species：

M/R,M/R

品牌：

萬物

購買數(shù)量：

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產(chǎn)品詳情操作說明注意事項(xiàng)

Product Information

Description	KMO rabbit polyclonal antibody
Protein full name	Kynurenine 3-monooxygenase
Synonyms	Kynurenine 3-hydroxylase, KMO
Immunogen	KLH conjugated Synthetic peptide corresponding to Mouse KMO
Isotype	IgG
Purity	Affinity purification
Subcellular location	Cytoplasm
Predicted MW.	55 kDa
Observed MW.	55 kDa
Uniprot ID	O15229, Q91WN4, O88867

Applications

Applications	Species	Dilution	Positive Sample
WB	Mouse, Rat	1: 500-1: 1000	stomach, heart, brain, cartilage
IHC/IF	Human, Rat	1: 1000-1: 6000	colon, esophagus, liver cancer, lung

Background

KMO(Kynurenine 3-monooxygenase) is an NADPH-dependent flavin monooxygenase, catalysing the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract.

Images

	Western blot analysis of KMO (GB111295) at dilution of 1: 500
	Immunohistochemistry of paraffin embedded human esophagus using KMO (GB111295) at dilution of 1: 900 (400x lens)
	Immunohistochemistry of paraffin embedded human liver cancer using KMO (GB111295) at dilution of 1: 900 (400x lens)
	Immunofluorescence of paraffin embedded human colon using KMO (GB111295) at dilution of 1: 1800 (400x lens)
	Immunofluorescence of paraffin embedded rat lung using KMO (GB111295) at dilution of 1: 1800 (400x lens)

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer.

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