Anti -RAB7 Rabbit pAb

價格：在線咨詢

貨號：

KT011966

產(chǎn)品規(guī)格：

100 μL

Applications：

Species：

HMR

品牌：

萬物

購買數(shù)量：

立即詢價在線咨詢 400-1016-218

產(chǎn)品詳情操作說明注意事項

Product Information

Description	RAB7 rabbit polyclonal antibody
Protein full name	Ras-related protein Rab-7a
Synonyms	Rab7a, RAB7
Immunogen	KLH conjugated Synthetic peptide corresponding to Mouse RAB7
Isotype	IgG
Purity	Affinity purification
Predicted MW.	23 kDa
Observed MW.	23 kDa
Uniprot ID	P51149, P51150, P09527

Applications

Applications	Species	Dilution	Positive Tissue
WB	Human, Mouse, Rat	1: 500-1: 1000	kidney, lung

Background

Key regulator in endo-lysosomal trafficking. Governs early-to-late endosomal maturation, microtubule minus-end as well as plus-end directed endosomal migration and positioning, and endosome-lysosome transport through different protein-protein interaction cascades. Plays a central role, not only in endosomal traffic, but also in many other cellular and physiological events.Also involved in regulation of some specialized endosomal membrane trafficking, such as maturation of melanosomes, pathogen-induced phagosomes (or vacuoles) and autophagosomes. Plays a role in the maturation and acidification of phagosomes that engulf pathogens. Plays a role in the fusion of phagosomes with lysosomes. Plays important roles in microbial pathogen infection and survival, as well as in participating in the life cycle of viruses. In concert with RAC1, plays a role in regulating the formation of RBs (ruffled borders) in osteoclasts.

Images

Western blot analysis of RAB7A (GB111190) at dilution of 1: 500

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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