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Anti -COX2 / Cyclooxygenase 2 Rabbit pAb

價格: 在線咨詢
貨號:
KT011963
產(chǎn)品規(guī)格:
100ul
Applications:
IHC/IF
Species:
H/M
購買數(shù)量:
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Product Information


Description

COX2 rabbit polyclonal antibody

Protein full name

Prostaglandin G/H synthase 2

Synonyms

PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2, prostaglandin-endoperoxide synthase 2

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse COX2

Isotype

IgG

Purity

Affinity purification

Subcellular location

Microsome membrane

Uniprot ID

Q05769, P35355



Applications


Applications

Species

Dilution

Positive Sample

IHC/IF

Human, Mouse

1: 500-1: 2000

cerebral infarction, colon cancer, stomach



Background


Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis.




Images




Immunohistochemistry of paraffin embedded human colon cancer using COX2 (GB11077-1) at dilution of 1:500 (400x lens)

Immunohistochemistry of paraffin embedded mouse stomach using COX2 (GB11077-1) at dilution of 1:500 (300x lens)

Immunofluorescence of paraffin embedded human colon cancer using COX2 (GB11077-1) at dilution of 1:1000 (300x lens)

Immunofluorescence of paraffin embedded mouse cerebral infarction using COX2 (GB11077-1) at dilution of 1:1000 (400x lens)




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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