Anti -LYVE1 Rabbit pAb

價(jià)格：在線咨詢

貨號：

KT011943

產(chǎn)品規(guī)格：

100 μL

Applications：

IHC/IF

Species：

品牌：

萬物

購買數(shù)量：

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產(chǎn)品詳情操作說明注意事項(xiàng)

Product Information

Description	LYVE1 rabbit polyclonal antibody
Protein full name	Lymphatic vessel endothelial hyaluronic acid receptor 1
Synonyms	LYVE-1, Cell surface retention sequence-binding protein 1, CRSBP-1, Extracellular link domain-containing protein 1, Hyaluronic acid receptor, CRSBP1, HAR, XLKD1
Immunogen	KLH conjugated Synthetic peptide corresponding to Mouse LYVE1
Isotype	IgG
Purity	Affinity purification
Subcellular location	Cell membrane
Uniprot ID	Q9Y5Y7

Applications

Applications	Species	Dilution	Positive Sample
IHC/IF	Human	1: 100-1: 800	colon, small intestine, tonsil

Background

LYVE1 has been identified as a major receptor for HA (extracellular matrix glycosaminoglycan hyaluronan) on the lymph vessel wall. The deduced amino acid sequence of LYVE1 predicts a 322-residue type I integral membrane polypeptide 41% similar to the CD44 HA receptor with a 212-residue extracellular domain containing a single Link module, the prototypic HA binding domain of the Link protein superfamily. Like CD44, the LYVE1 molecule binds both soluble and immobilized HA. However, unlike CD44, the LYVE1 molecule colocalizes with HA on the luminal face of the lymph vessel wall and is completely absent from blood vessels. Hence, LYVE1 is the first lymph-specific HA receptor to be characterized and is a uniquely powerful marker for lymph vessels themselves.

Images

	Immunohistochemistry of paraffin embedded human colon using lyve-1 (GB111689) at dilution of 1:400 (400x lens)
	Immunohistochemistry of paraffin embedded human small intestine using lyve-1 (GB111689) at dilution of 1:400 (400x lens)
	Immunohistochemistry of paraffin embedded human tonsil using lyve-1 (GB111689) at dilution of 1:400 (400x lens)

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer	PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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