Anti -LIMK1 Rabbit pAb

價格：在線咨詢

貨號：

KT011722

產(chǎn)品規(guī)格：

100 μL

Applications：

IHC/IF

Species：

H/M/R

品牌：

萬物

購買數(shù)量：

立即詢價在線咨詢 400-1016-218

產(chǎn)品詳情操作說明注意事項(xiàng)

Product Information

Description	LIMK1 rabbit polyclonal antibody
Protein full name	LIM domain kinase 1
Synonyms	LIMK1, KIZ-1, LIM motif-containing protein kinase
Immunogen	Recombinant protein corresponding to Mouse LIMK1
Isotype	IgG
Purity	Affinity purification
Subcellular location	Cytoplasm, Nucleus
Uniprot ID	P53668, P53669

Applications

Applications	Species	Dilution	Positive Sample
IHC/IF	Human, Mouse, Rat	1: 750-1: 4000	breast cancer, lung, spinal cord, testis

Background

LIMK1, a member of the Ser/Thr protein kinase family, may be a component of an intracellular signaling pathway and may be involved in brain development. It phosphorylates and inactivates the actin binding/depolymerizing factor cofilin and induces actin cytoskeletal changes. The LIM domain interacts with the cytoplasmic domain of NRG1, and this cytoplasmic protein also binds ROCK1, which phosphorylates LIMK1 on serine and/or threonine residues. Highest expression occurs in both adult and fetal nervous systems.

Images

	Immunohistochemistry of paraffin embedded mouse lung using Limk (GB11994) at dilution of 1:2000 (250x lens)
	Immunohistochemistry of paraffin embedded rat testis using Limk (GB11994) at dilution of 1:2000 (200x lens)
	Immunohistochemistry of paraffin embedded rat lung using Limk (GB11994) at dilution of 1:2000 (250x lens)
	Immunofluorescence of paraffin embedded human breast cancer using Limk (GB11994) at dilution of 1:1500 (250x lens)
	Immunofluorescence of paraffin embedded mouse spinal cord using Limk (GB11994) at dilution of 1:1500 (300x lens)
	Immunofluorescence of paraffin embedded rat testis using Limk (GB11994) at dilution of 1:1500 (200x lens)
	Immunofluorescence of paraffin embedded rat lung using Limk (GB11994) at dilution of 1:1500 (250x lens)

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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