Anti -Synaptopodin Rabbit pAb

價(jià)格：在線咨詢

貨號(hào)：

KT011603

產(chǎn)品規(guī)格：

100 μL

Applications：

Species：

M/R

品牌：

萬物

購買數(shù)量：

立即詢價(jià) 在線咨詢 400-1016-218

產(chǎn)品詳情操作說明注意事項(xiàng)

Product Information

Description	Synaptopodin rabbit polyclonal antibody
Protein full name	Synaptopodin
Synonyms	Synpo, Kiaa1029, SYNPO
Immunogen	Recombinant protein corresponding to Mouse Synaptopodin
Isotype	IgG
Purity	Affinity purification
Predicted MW.	100 kDa
Observed MW.	100 kDa
Uniprot ID	Q8CC35, Q9Z327

Applications

Applications	Species	Dilution	Positive Sample
WB	Mouse, Rat	1: 500-1: 800	cerebral cortex, brain, skeletal muscle, cerebellum

Background

Actin-associated protein that may play a role in modulating actin-based shape and motility of dendritic spines and renal podocyte foot processes. Seems to be essential for the formation of spine apparatuses in spines of telencephalic neurons, which is involved in synaptic plasticity.SYNPO, also known as synaptopodin, is an actin-associated protein in telencephalic dendrites and renal podocytes. SYNPO is tightly associated with the dendritic spine apparatus, and mice lacking the SYNPO gene lack the apparatus. These SYNPO-null mice also demonstrate an impaired ability to express long-term potentiation as well as deficits in spatial memory tasks, indicating that SYNPO is involved in the regulation of synaptic plasticity. Recent studies suggest that SYNPO is linked to neuronal calcium stores and plays a role in the calcium store-associated ability of neurons to undergo long-term plasticity.

Images

Picture 1.png

Western blot analysis of Synaptopodin (GB111379) at dilution of 1: 500

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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