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Anti -ZAP70 Rabbit pAb

價(jià)格: 在線咨詢
貨號(hào):
DRF101939
產(chǎn)品規(guī)格:
100 μL
Applications:
Species:
購(gòu)買(mǎi)數(shù)量:
產(chǎn)品詳情 操作說(shuō)明 注意事項(xiàng)

Product Information


Description

ZAP70 rabbit polyclonal

Protein full name

Tyrosine-protein kinase ZAP-70

Synonyms

70 kDa zeta-chain associated protein, Syk-related tyrosine kinase, Zap70, Srk, Zap-70

Immunogen

Recombinant protein corresponding to Mouse ZAP70

Isotype

IgG

Purity

Affinity purification

Predicted MW.

70 kDa

Observed MW.

70 kDa

Uniprot ID

P43403, P43404




Applications


Applications

Species

Dilution

Positive Tissue

WB

Human, Mouse, Rat

1: 500-1: 1000

lymph nodes, thymus, spleen




Background


This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells.




Images


Western blot analysis of ZAP70 (GB111128) at dilution of 1: 1000
Lane 1: Jurkat cell lysate
Lane 2: Mouse lymph nodes tissue lysate
Lane 3: Mouse thymus tissue lysate
Lane 4: Mouse spleen tissue lysate
Lane 5: Rat lymph nodes tissue lysate
Lane 6: Rat thymus tissue lysate




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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