Anti -CD11b Rabbit pAb

價格：在線咨詢

貨號：

DRF101803

產(chǎn)品規(guī)格：

100 μL

Applications：

Species：

品牌：

萬物

購買數(shù)量：

立即詢價在線咨詢 400-1016-218

產(chǎn)品詳情操作說明注意事項

Product Information

Description	CD11b rabbit polyclonal
Protein full name	Integrin alpha-M
Synonyms	ITGAM, CD11B, CR3A, MAC-1, MAC1A, MO1A, SLEB6, integrin subunit alpha M
Immunogen	KLH conjugated Synthetic peptide corresponding to Mouse CD11b
Isotype	IgG
Purity	Affinity purification
Subcellular location	Membrane
Uniprot ID	P05555

Applications

applications	species	dilution	Positive tissue
IHC	Mouse, Rat	1: 500-1: 1000	septic lung, spleen
IF	Mouse, Rat	1: 500-1: 1000	septic lung

Background

This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene.

Images

	Immunohistochemistry analysis of paraffin-embedded mouse septic lung using CD11b(GB11058) at dilution of 1: 500
	Immunohistochemistry analysis of paraffin-embedded rat septic lung using CD11b(GB11058) at dilution of 1: 500
	Immunohistochemistry analysis of paraffin-embedded mouse spleen using CD11b(GB11058) at dilution of 1: 500
	Immunofluorescent analysis of paraformaldehyde-fixed mouse septic lung using CD11b(GB11058) at dilution of 1: 500

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

Publications:

	Title	Journal	Pubmed ID	Application
1	Necroptosis is active and contributes to intestinal injury in a piglet model with lipopolysaccharide challenge.	Cell Death & Disease	33431831	IHC
2	Loss of natural resistance to schistosome in T cell deficient rat.	PLoS Neglected Tropical Diseases	33347431	IHC
3	Long-term inhibition of dipeptidyl-peptidase 4 reduces islet infiltration and downregulates IL-1β and IL-12 in NOD mice.	International Immunopharmacology	33182020	IHC
4	Involvement of kindlin-2 in irisin's protection against ischaemia reperfusion-induced liver injury in high-fat diet-fed mice.	Journal of Cellular and Molecular Medicine	32954626	IHC，IF
5	Optimization Strategy for Generating Gene-edited Tibet Minipigs by Synchronized Oestrus and Cytoplasmic Microinjection.	International Journal of Biological Sciences	31754342	IHC
6	MMI-0100 Ameliorates Dextran Sulfate Sodium-Induced Colitis in Mice through Targeting MK2 Pathway.	Molecules (Basel, Switzerland)	31382637	IF

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