Anti -CD163 Rabbit pAb

價(jià)格：在線咨詢

貨號：

DRF101795

產(chǎn)品規(guī)格：

100 μL

Applications：

Species：

品牌：

萬物

購買數(shù)量：

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產(chǎn)品詳情操作說明注意事項(xiàng)

Product Information

Description	CD163 rabbit polyclonal
Protein full name	Scavenger receptor cysteine-rich type 1 protein M130
Synonyms	CD163, M130, MM130, SCARI1, CD163 molecule
Immunogen	Recombinant protein corresponding to Mouse CD163
Isotype	IgG
Purity	Affinity purification
Predicted MW.	125 kDa
Observed MW.	145 kDa
Uniprot ID	Q2VLH6, Q86VB7

Applications

applications	species	dilution	Positive tissue
WB	Human, Mouse, Rat	1: 1200-1: 1500	spleen, lung, lymph nodes

Background

Involved in clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages and may thereby protect tissues from free hemoglobin-mediated oxidative damage. May play a role in the uptake and recycling of iron, via endocytosis of hemoglobin/haptoglobin and subsequent breakdown of heme. Binds hemoglobin/haptoglobin complexes in a calcium-dependent and pH-dependent manner. Induces a cascade of intracellular signals that involves tyrosine kinase-dependent calcium mobilization, inositol triphosphate production and secretion of IL6 and CSF1 (By similarity).

Images

Western blot analysis of CD163 (GB11340) at dilution of 1:1200.

Lane 1:MH-S cell lysate

Lane 2:Raw264.7 cell lysate

Lane 3:Mouse spleen tissue lysate

Lane 4:Mouse lung tissue lysate

Lane 5:Mouse lymph nodes tissue lysate

Lane 6:Rat lung tissue lysate

Western blot analysis of CD163 (GB11340) at dilution of 1:1200.

Lane 1:SH-SY5Y cell lysate

Lane 2:THP-1 cell lysate

Lane 3:Raw264.7 cell lysate

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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