Anti -CD68 Rabbit pAb

價(jià)格：在線咨詢

貨號：

DRF101787

產(chǎn)品規(guī)格：

100 μL

Applications：

Species：

品牌：

萬物

購買數(shù)量：

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產(chǎn)品詳情操作說明注意事項(xiàng)

Product Information

Description	CD68 rabbit polyclonal
Protein full name	Macrosialin
Synonyms	CD68,CD68 Molecule,Scavenger Receptor Class D, Member 1 ,Macrophage Antigen CD68,GP110 ,Macrosialin,SCARD1, LAMP4
Immunogen	KLH conjugated Synthetic peptide corresponding to Mouse CD68
Isotype	IgG
Purity	Affinity purification
Subcellular location	Cell membrane,Endosome membrane, Lysosome membrane
Uniprot ID	P31996

Applications

applications	species	dilution	Positive tissue
IHC	Mouse, Rat	1: 300-1: 1000	hepatitis, spleen, lung, liver
IF	Mouse, Rat	1: 500-1: 1000	spleen

Background

Could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells.

Images

	Immunohistochemistry analysis of paraffin-embedded mouse hepatitis using CD68 (GB11067) at dilution of 1: 500
	Immunohistochemistry analysis of paraffin-embedded mouse spleen using CD68 (GB11067) at dilution of 1: 500
	Immunohistochemistry analysis of paraffin-embedded mouse lung using CD68 (GB11067) at dilution of 1: 500
	Immunohistochemistry analysis of paraffin-embedded mouse liver using CD68 (GB11067) at dilution of 1: 500
	Immunofluorescent analysis of paraformaldehyde-fixed rat spleen using CD68 (GB11067) at dilution of 1: 500
	Immunofluorescent analysis of paraformaldehyde-fixed mouse bone using CD68(GB11067) at dilution of 1:1000
	Immunohistochemistry analysis of paraffin-embedded rat lymph node using CD68(GB11067) at dilution of 1:1000
	Immunohistochemistry analysis of paraffin-embedded rat spleen using CD68(GB11067) at dilution of 1:1000

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

Publications:

	Title	Journal	Pubmed ID	Application
1	Silencing COX-2 blocks PDK1/TRAF4-induced AKT activation to inhibit fibrogenesis during skeletal muscle atrophy.	Redox Biology	33152664	IHC
2	Single-cell RNA-Seq reveals the transcriptional landscape and heterogeneity of skin macrophages in Vsir-/- murine psoriasis.	Theranostics	32929361	IHC
3	Anti-Atherosclerosis Effect of Angong Niuhuang Pill via Regulating Th17/Treg Immune Balance and Inhibiting Chronic Inflammatory on ApoE-/- Mice Model of Early and Mid-Term Atherosclerosis.	Frontiers in Pharmacology	32082145	IHC
4	Gaudichaudione H Inhibits Inflammatory Responses in Macrophages and Dextran Sodium Sulfate-Induced Colitis in Mice.	Frontiers in Pharmacology	32009962	IHC
5	Human amnion mesenchymal stem cells attenuate atherosclerosis by modulating macrophage function to reduce immune response.	International Journal of Molecular Medicine	31364743	IHC
6	IL-17A Can Promote Propionibacterium acnes-Induced Sarcoidosis-Like Granulomatosis in Mice.	Frontiers in Immunology	31474992	IHC
7	C1q/TNF-related protein-9 promotes macrophage polarization and improves cardiac dysfunction after myocardial infarction.	Journal of Cellular Physiology	30953351	IF
8	Galectin-3 Mediates Endothelial-to-Mesenchymal Transition in Pulmonary Arterial Hypertension.	Aging and Disease	31440380	IHC
9	Carotid baroreceptor stimulation in obese rats affects white and brown adipose tissues differently in metabolic protection.	Journal of Lipid Research	31126973	IHC
10	CXCL12/CXCR4 promotes inflammation-driven colorectal cancer progression through activation of RhoA signaling by sponging miR-133a-3p.	Journal of Experimental & Clinical Cancer Research : CR	30678736	IHC/IF

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