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Anti -TLR4 Rabbit pAb

價格: 在線咨詢
貨號:
DRF101759
產品規(guī)格:
100 μL
Applications:
Species:
購買數量:
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Product Information


Description

TLR4 rabbit polyclonal

Protein full name

Toll-like receptor 4

Synonyms

TLR4, ARMD10, CD284, TLR-4, TOLL,

toll like receptor 4

Immunogen

KLH conjugated Synthetic peptide

corresponding to Mouse TLR4.

Isotype

IgG

Purity

Affinity purification

Predicted MW.

95 KDa

Observed MW.

95 KDa

Subcellular location

Membrane

Uniprot ID

Q9QUK6, Q9QX05, O00206



Applications


applications

species

dilution

Positive tissue

WB

Human, Mouse, Rat

1: 500-1: 1000

spleen, lung, thymus

IHC

Human, Mouse, Rat

1: 1000-1: 2000

immune spleen

IF

Human, Mouse, Rat

1: 300-1: 1000

tonsil, septic spleen, lymph node, spleen



Background


A member of the toll-like receptor (TLR) family, which plays a fundamental

role in pathogen recognition and activation of innate immunity. It

cooperates with LY96 (also referred as MD-2) and CD14 to mediate

in signal transduction events induced by lipopolysaccharide (LPS) found

in most gram-negative bacteria. Mutations in this gene have been

associated with differences in LPS responsiveness. TLR4 signaling

responds to signals by forming a complex using an extracellular

leucine-rich repeat domain (LRR) and an intracellular toll/interleukin-1

receptor (TIR) domain.




Images



圖片 1.png

Western blot analysis of TLR4 (GB11519) at dilution of 1:1000

Immunohistochemistry analysis of paraffin-embedded mouse immune spleen using TLR4 (GB11519) at dilution of 1:1000

Immunohistochemistry analysis of paraffin-embedded rat immune spleen using TLR4 (GB11519) at dilution of 1:1000

Immunofluorescent analysis of paraffin-embedded human tonsil using 

TLR4 (GB11519) at dilution of 1:1000

Immunofluorescent analysis of paraffin-embedded mouse septic spleen using TLR4 (GB11519) at dilution of 1:1000

Immunofluorescent analysis of paraffin-embedded rat septic spleen using 

TLR4 (GB11519) at dilution of 1:1000


Immunofluorescent analysis of paraffin-embedded rat lymph node using TLR4 (GB11519) at dilution of 1:1000

Immunofluorescent analysis of paraffin-embedded rat spleen using 

TLR4 (GB11519) at dilution of 1:1000





Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .


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