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Anti -FGL2/Prothrombinase Rabbit pAb

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貨號:
DRF101739
產(chǎn)品規(guī)格:
100 μL
Applications:
Species:
購買數(shù)量:
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Product Information


Description FGL2/Prothrombinase rabbit polyclonal
Protein full name Fibroleukin
Synonyms Cytotoxic T-lymphocyte-specific protein, Fibrinogen-like protein 2, Prothrombinase, Fgl2, Fiblp, pT49, T49, fibrinogen like 2
Immunogen Recombinant protein corresponding to Mouse FGL2/Prothrombinase
Isotype IgG
Purity Affinity purification
Predicted MW. 49 kDa
Observed MW. 64 kDa
Uniprot ID Q14314




Applications


Applications Species Dilution Positive Tissue
WB Human 1: 500-1: 1000 Raji, HepG2, SW480




Background

FGL2 (fibrinogen like protein 2) is a 70 kDa glycoprotein that belongs to the fibrinogen-related superfamily of proteins which are involved in coagulation, cell adhesion, and transendothelial migration. FGL2 is an important immune regulator of both innate and adaptive response. It is present on the surface of macrophages and endothelial cells, and can be constitutively secreted by CD4+ CD8+ T cell. FGL2 forms a tetrameric complex which is stabilized by interchain disulfide bonds and it exerts immunosuppressive effects on both T cell proliferation and dendritic cell maturation. The protein may play a role in physiologic functions at mucosal sites.




Images



Western blot analysis of FGL2 (GB111587)
at dilution of 1: 1000
Lane 1: Raji cell lysate
Lane 2: HepG2 cell lysate
Lane 3: SW480 cell lysate




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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