Anti -TLR2 Rabbit pAb

價(jià)格：在線咨詢

貨號(hào)：

DRF101757

產(chǎn)品規(guī)格：

100 μL

Applications：

Species：

品牌：

萬(wàn)物

購(gòu)買數(shù)量：

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產(chǎn)品詳情操作說(shuō)明注意事項(xiàng)

Product Information

Description	TLR2 rabbit polyclonal
Protein full name	Toll-like receptor 2
Synonyms	TLR2, CD282, TIL4, toll like receptor 2, Toll/interleukin receptor like protein 4, TIL4
Immunogen	KLH conjugated Synthetic peptide corresponding to Mouse TLR2
Isotype	IgG
Purity	Affinity purification
Subcellular location	Membrane
Uniprot ID	O60603, Q9QUN7

Applications

Applications	Species	Dilution	Positive Tissue
IHC	Human, Mouse	1: 500-1: 1000	ovarian cancer, appendix, liver, lung
IF	Human, Mouse	1: 500-1: 1000	tonsil, cervical cancer

Background

TLR2 is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities, while the various TLRs exhibit different patterns of expression. This gene is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-κB. In the intestine, TLR2 regulates the expression of CYP1A1, which is a key enzyme in detoxication of carcinogenic polycyclic aromatic hydrocarbons such as benzo(a)pyrene.

Images

	Immunohistochemistry analysis of paraffin-embedded human ovarian cancer using TLR2 (GB113378) at dilution of 1: 1000
	Immunohistochemistry analysis of paraffin-embedded human appendix using TLR2 (GB113378) at dilution of 1: 1000
	Immunohistochemistry analysis of paraffin-embedded mouse liver with LPS treated for 6h using TLR2 (GB113378) at dilution of 1: 1000
	Immunohistochemistry analysis of paraffin-embedded mouse lung with LPS treated for 12h using TLR2 (GB113378) at dilution of 1: 1000
	Immunofluorescent analysis of paraformaldehyde-fixed human cervical cancer using TLR2 (GB113378) at dilution of 1: 1000
	Immunofluorescent analysis of paraformaldehyde-fixed human tonsil using TLR2 (GB113378) at dilution of 1: 1000

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer	PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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