Anti -GAPDH Mouse mAb

價(jià)格：在線咨詢

貨號：

DRF10112

產(chǎn)品規(guī)格：

100 μL

Applications：

Species：

H,M,R

品牌：

萬物

購買數(shù)量：

立即詢價(jià) 在線咨詢 400-1016-218

產(chǎn)品詳情操作說明注意事項(xiàng)

Product Information

Description	alpha Actinin rabbit polyclonal
Protein full name	Alpha-actinin-1
Synonyms	Alpha-actinin cytoskeletal isoform, F-actin cross-linking protein, actinin, Non-muscle alpha-actinin-1, ACTN1, actinin 1 smooth muscle, Actn1a, BDPLT15, I79_004057
Immunogen	Recombinant protein corresponding to Mouse α-actinin1
Isotype	IgG
Purity	Affinity purification
Predicted MW.	103 kDa
Observed MW.	103 kDa
Uniprot ID	Q7TPR4, P12814, Q9Z1P2

Applications

Applications	Species	Dilution	Positive Tissue
WB	Human, Mouse, Rat	1: 2000-1: 4000	lung, stomach, colon, hysteromyoma

Background

Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found alongmicrofilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene.

Images

圖片 1.png

Western blot analysis of α-actinin (GB11230) at dilution of 1: 2000.

Lane 1: HepG2 cell lysate

Lane 2: AN3CA cell lysate

Lane 3: Human hysteromyoma tissue lysate

Lane 4: Mouse lung tissue lysate

Lane 5: Mouse stomach tissue lysate

Lane 6: Mouse colon tissue lysate

Lane 7: Rat lung tissue lysate

Lane 8: Rat stomach tissue lysate

Lane 9: Rat colon tissue lysate

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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