Anti -NDP Rabbit pAb

價格：在線咨詢

貨號：

KT012223

產(chǎn)品規(guī)格：

100 μL

Applications：

Species：

M/R

品牌：

萬物

購買數(shù)量：

立即詢價在線咨詢 400-1016-218

產(chǎn)品詳情操作說明注意事項

Product Information

Description	NDP rabbit polyclonal antibody
Protein full name	Norrin
Synonyms	Norrie disease protein homolog, Ndp, Ndph, FEVR, EVR2, X linked exudative vitreoretinopathy 2 protein
Immunogen	KLH conjugated Synthetic peptide corresponding to Mouse NDP
Isotype	IgG
Purity	Affinity purification
Predicted MW.	15 kDa
Observed MW.	15 kDa
Uniprot ID	P48744

Applications

Applications	Species	Dilution	Positive Tissue
WB	Mouse, Rat	1: 500-1: 1000	brain, testis, liver

Background

NDP, also named as EVR2, ND and Norrin, is a secreted regulatory protein that remains tightly associated with the extracellular matrix. Mutations in the NDP gene are associated with the Norrie disease. Signaling induced by the protein NDP regulates vascular development of vertebrate retina and controls important blood vessels in the ear. It binds with high affinity to Frizzled 4, and Frizzled 4 knockout mice exhibit abnormal vascular development of the retina.

Images

Western blot analysis of Ndp (GB112642) at dilution of 1: 500

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer	PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.

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