Anti -MAPRE1/EB1 Rabbit pAb

價(jià)格：在線咨詢

貨號(hào)：

KT011859

產(chǎn)品規(guī)格：

100ul

Applications：

Species：

H/M

品牌：

萬物

購(gòu)買數(shù)量：

立即詢價(jià) 在線咨詢 400-1016-218

產(chǎn)品詳情操作說明注意事項(xiàng)

Product Information

Description	EB1 rabbit polyclonal antibody
Protein full name	Microtubule-associated protein RP/EB family member 1
Synonyms	APC-binding protein EB1, End-binding protein 1, EB1, Mapre1
Immunogen	Recombinant protein corresponding to Mouse EB1
Isotype	IgG
Purity	Affinity purification
Predicted MW.	30 kDa
Observed MW.	35 kDa
Uniprot ID	Q61166

Applications

Applications	Species	Dilution	Positive Tissue
WB	Human, Mouse	1: 500-1: 1000	colon, thymus, liver, kidney

Background

The EB1 protein Plus-end tracking protein (+TIP) that binds to the plus-end of microtubules and regulates the dynamics of the microtubule cytoskeleton. Promotes cytoplasmic microtubule nucleation and elongation. May be involved in spindle function by stabilizing microtubules and anchoring them at centrosomes. Also acts as a regulator of minus-end microtubule organization: interacts with the complex formed by AKAP9 and PDE4DIP, leading to recruit CAMSAP2 to the Golgi apparatus, thereby tethering non-centrosomal minus-end microtubules to the Golgi, an important step for polarized cell movement. Promotes elongation of CAMSAP2-decorated microtubule stretches on the minus-end of microtubules. Acts as a regulator of autophagosome transport via interaction with CAMSAP2 (By similarity). May play a role in cell migration.

Images

Picture 1.png

Western blot analysis of EB1 (GB111069) at dilution of 1: 500

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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