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Anti -Spry-2 Rabbit pAb

價格: 在線咨詢
貨號:
KT011791
產(chǎn)品規(guī)格:
100ul
Applications:
WB
Species:
H/M/R
購買數(shù)量:
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Product Information


Description

Spry-2 rabbit polyclonal antibody

Protein full name

Protein sprouty homolog 2

Synonyms

SPRY2, hIGAN3, sprouty RTK signaling antagonist 2, hSPRY2, Protein sprouty homolog 2, Spry-2

Immunogen

Recombinant protein corresponding to Mouse Spry-2

Isotype

IgG

Purity

Affinity purification

Predicted MW.

35 kDa

Observed MW.

35 kDa

Uniprot ID

O43597, Q9QXV8




Applications


Applications

Species

Dilution

Positive Tissue

WB

Human, Mouse, Rat

1: 500-1: 1000

heart, lung, brain




Background


Sprouty was originally identified as an inhibitor of Drosophila epidermal growth factor (EGF) and fibroblast growth factor (FGF) receptor signaling during tracheal development. Four isoforms of mammalian sprouty are known (Spry1-Spry4). The role of the mammalian analogs has not been clearly elucidated although it is believed that human Sprouty 2 (hSpry2) may be an inhibitor of cellular migration and proliferation. Spry2 and Spry4 show considerable sequence homology between human and mouse at the C terminus of the protein. Significant sequence divergence occurs at the N terminus. Spry2 appears to be abundant in brain, lung and heart tissue, with lesser amounts found in kidney and skeletal muscle.




Images



Picture 1.png

Western blot analysis of SPY2 (GB11860) at dilution of 1: 500





Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer.

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