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Anti -SYT1 Mouse mAb

價(jià)格：在線咨詢(xún)

貨號(hào)：

KT011505

產(chǎn)品規(guī)格：

100 μL

Applications：

Species：

H,M,R

品牌：

萬(wàn)物

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產(chǎn)品詳情操作說(shuō)明注意事項(xiàng)

Product Information

Description	SYT1 mouse monoclonal antibody
Protein full name	Synaptotagmin-1
Synonyms	Synaptotagmin I, SytI, p65, DKFZp781D2042, FLJ42519, SVP65, Syt2
Immunogen	Recombinant protein corresponding to Mouse SYT1
Isotype	IgG
Purity	Affinity purification
Predicted MW.	47 kDa
Observed MW.	60 kDa
Uniprot ID	P21579, P46096

Applications

Applications	Species	Dilution	Positive Sample
WB	Human, Mouse, Rat	1: 500-1: 1000	brain, cerebral cortex, cerebellum

Background

Synaptotagmin 1 is a synaptic vesicle membrane glycoprotein that is widely expressed throughout the CNS and is generally thought to act as the Ca2+ sensor in the regulation of exocytosis and neurotransmitter release. Studies indicate that synaptotagmin's Ca2+ mediated binding of SNAP25 is essential for the Ca2+ dependent triggering of membrane. Synaptotagmin 1 may have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. Further, Synaptotagmin 1 binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca(2+)-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has been reported.

Images

Picture 1.png

Western blot analysis of SYT1 (GB121130) at dilution of 1: 1000

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer	PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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