Anti -CD3 Rabbit mAb

價格：在線咨詢

貨號：

DRF101780

產(chǎn)品規(guī)格：

50 μL

Applications：

Species：

品牌：

萬物

購買數(shù)量：

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產(chǎn)品詳情操作說明注意事項

Product Information

Description	CD3 rabbit monoclonal
Protein full name	T-cell surface glycoprotein CD3 epsilon chain
Synonyms	CD3E, IMD18, T3E, TCRE, CD3e molecule
Immunogen	KLH conjugated Synthetic peptide corresponding to human CD3 epsilon
Isotype	IgG
Purity	Affinity purification
Subcellular location	Cell membrane
Uniprot ID	P07766

Applications

applications	species	dilution	Positive tissue
IHC	Human, Mouse, Rat	1: 50-1: 200	spleen, liver
IF	Human, Mouse, Rat	1: 50-1: 200	spleen, liver

Background

The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women.

Images

Immunohistochemistry analysis of paraffin-embedded human spleen using CD3(GB13014) at dilution of 1:100.

Immunohistochemistry analysis of paraffin-embedded mouse liver using CD3(GB13014) at dilution of 1:100.

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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