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Anti -CCR3 Rabbit pAb

價(jià)格: 在線咨詢
貨號(hào):
DRF101716
產(chǎn)品規(guī)格:
100 μL
Applications:
Species:
購(gòu)買數(shù)量:
產(chǎn)品詳情 操作說(shuō)明 注意事項(xiàng)

Product Information


Description

CCR3 rabbit polyclonal

Protein full name

Probable C-C chemokine receptor type 3

Synonyms

C-C CKR-3, CC-CKR-3, CCR-3, CCR3, CKR3, Macrophage inflammatory protein 1-alpha receptor-like 2, IP-1 alpha RL2, CD193, Ccr3, Cmkbr1l2, Cmkbr3

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse CCR3

Isotype

IgG

Purity

Affinity purification

Predicted MW.

42 kDa

Observed MW.

50 kDa

Uniprot ID

P51678




Applications


Applications

Species

Dilution

Positive Tissue

WB

Mouse

1: 300-1: 600

liver




Background


The protein encoded by this gene is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3(CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21.




Images


圖片 1.png

Western blot analysis of CCR3 (GB112453) 

at dilution of 1: 600

Lane 1: Mouse liver tissue lysate




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .


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