Anti -TSLP Rabbit pAb

價格：在線咨詢

貨號：

DRF101657

產(chǎn)品規(guī)格：

100 μL

Applications：

Species：

品牌：

萬物

購買數(shù)量：

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產(chǎn)品詳情操作說明注意事項

Product Information

Description	TSLP rabbit polyclonal
Protein full name	Thymic stromal lymphopoietin
Synonyms	Thymic stroma-derived lymphopoietin, Tslp, TSLP protein, thymic stromal lymphopoietin
Immunogen	Recombinantproteincorrespondingto Mouse TSLP
Isotype	IgG
Purity	Affinity purification
Subcellular location	Secreted
Uniprot ID	Q9JIE6

Applications

Applications	Species	Dilution	Positive Tissue
IHC	Mouse, Rat	1: 500-1: 1500	lung, brain, skin, heart
IF	Mouse, Rat	1: 500-1: 1000	prostate, lung

Background

TSLP is a 159 amino acid four helix-bundle hemopoietic cytokine that signals through a heterodimeric receptor complex consisting of the human TSLP receptor and the IL-7R alpha-chain. It impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes, enhances the maturation of CD11c ( ) dendritic cells, naive CD4 ( ), and CD8 ( ) T cells into proallergic effectors, and primes dendritic cells to produce large amounts of IL-12 after CD40 ligand stimulation. TSLP influences the regulation of the positive selection of regulatory T cells and maintenance of peripheral CD4 ( ) T cell homeostasis. It induces allergic inflammation by directly activating mast cells and may be involved in the pathophysiology of inflammatory arthritis.

Images

	Immunohistochemistry analysis of paraffin-embedded mouse lung using TSLP(GB111664) at dilution of 1: 1000
	Immunohistochemistry analysis of paraffin-embedded rat lung using TSLP(GB111664) at dilution of 1: 1000
	Immunohistochemistry analysis of paraffin-embedded mouse brain using TSLP(GB111664) at dilution of 1: 1000
	Immunohistochemistry analysis of paraffin-embedded rat brain using TSLP(GB111664) at dilution of 1: 1000
	Immunohistochemistry analysis of paraffin-embedded mouse skin using TSLP(GB111664) at dilution of 1: 1000
	Immunohistochemistry analysis of paraffin-embedded rat skin using TSLP(GB111664) at dilution of 1: 1000
	Immunohistochemistry analysis of paraffin-embedded rat skin using TSLP(GB111664) at dilution of 1: 1000
	Immunohistochemistry analysis of paraffin-embedded rat heart using TSLP(GB111664) at dilution of 1: 1000
	Immunofluorescent analysis of paraformaldehyde-fixed mouse prostate using TSLP (GB111664) at dilution of 1: 650
	Immunofluorescent analysis of paraformaldehyde-fixed rat lung using TSLP (GB111664) at dilution of 1: 650

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer	PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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